Acne is affecting 50 million Americans and the cost of the treatment plus work loss estimate to 3 billion dollars (2016-2026).
The fact that Vitamin-D is good for acne is supported by research with compelling scientific pieces of evidence.
The blog will be about:
- A synopsis on Vitamin-D and Acne
- Effect of Vitamin-D Deficiency -Cause of Acne
- Vitamin-D for Acne- The Benefits
- Tips to Increase Your Vitamin-D level
a) Sun exposure, b) Vitamin-D supplements, c) Vitamin-D rich food, d) Topical application of Vitamin-D
5. Take Away
A synopsis on Vitamin-D and Acne
Vitamin-D is produced on skin by sun exposure and fondly known as “sunshine” Vitamin. It is a prohormone and converted to hormone inside the body. Vit-D in its hormone form performs and controls multiple operations in the body. Vitamin-D deficiency is associated with several skins and other diseases, many of them are life-threatening.
Acne is a skin disfiguring disorder characterized by different types of bumps on the skin surface. These are clogged pores with oil, a massive number of dead skin cells and may contain parasitic bacteria. They can be painful depending on the severity.
Let’s find out how Vitamin-D benefits acne and the cause in this important and disturbing skin disorder.
Effect of Vitamin-D Deficiency- Cause of Acne
Hormones work together. Vitamin-D deficiency is a hormonal deficiency that affects other hormones creating an imbalance. It is connected with poor health of the endocrine system that results in skin disorder.
From observational studies, Vitamin-D deficiency has been suggested to increase acne causing androgen, testosterone level and POC (March 2018). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854850/
Increased level of androgen stimulates the sebaceous gland to force release excess oil. This situation leads to hyperproliferation of cells and massive shedding of cells leading to the clogging of the pore.
To make this situation worse, the hormone imbalance results in a disturbance in the health of microbial equilibrium where P. acne is an inhabitant. The acne microbes get into the acne site creating inflammation.
Overall it is a cascade effect.
Deficiency of Vitamin-D is associated with increased susceptibility to infection. Multiple studies in adults and children have demonstrated that vitamin D deficiency is associated with increased risk and greater severity of an infection.
Researchers have found <15 ng/ mL vitamin-D (Vitamin-D deficiency) have found a high level of inflammatory response
Vitamin-D for Acne and Clear Skin- The Benefits
First off, adequate Vitamin-D serum level keeps the hormones in harmony and help to hinder the onset of acne
Here is some attribute of Vitamin-D that is essential for being anti-acne.
- It is a controller of the hormone system
- It is involved in cell growth, proliferation and orderly renewal of skin
- It regulates sebum production
- The modulator of the Immune System.
It influences the production of important endogenous antimicrobial peptides such as cathelicidin, and regulate the inflammatory cascade.
5. Vitamin-D deficiency is associated with Inflammation. At Vit-D serum level of 50 ng/ mL, the highest level of inflammatory inhibition was found.
6. It has a strong anti-microbial action
7. It helps regulate microbial balance, where P. Acne is an inhabitant.
In a 2016 study with 160 subjects (80 having acne and 80 having number acne), 22.5% of number-acne and 48.8% were found to be vitamin-D deficient. The severity of the disease in the study arm was found to be related to the amount of Vit-D. The less the D-amount, the worse was the severity. Treating the subjects with Vit-D with 1000 IU/ day for of Vit-D improved the severity and inflammation of 39% of the subjects.
Consolidation all the above points tend toward an adequate level of Vitamin-D can influence and help acne offering you clearer skin inside out.
Tips to Increase Your Vitamin-D level
Sun exposure: This is the major source of Vitamin-D. With all these major compelling evidence and testimonials mounting about the association of vitamin-D deficiency with acne, wise sun exposure provides one of the most effective treatment options for acne. Repeated and frequent sun exposure within a period can provide you maximum benefit with minimum exposure
Topical Vitamin-D for Acne
In a trial to evaluating the feasibility of transdermal delivery of Vitamin-D consisting of 48 women, it is demonstrated that the topical application of vitamin-D could increase the Vitamin-D level.
Topical Application of Vitamin-D Enhances the Vitamin-D Level
|Topical Application of Vitamin-D Enhances the Vitamin-D Level|
|Control Arm||Study Arm|
|No of subjects*||24||24|
|Starting Vit-D level in ng/ mL||10.4 ± 3.97**||12.85± 6.54 **|
|Treatment regimen||Aloe vera gel||Vitamin-D3 + Aloe vera gel|
|Amount of Aloe vera gel||1 g||1 gm ( + 5000 IU of Vit-D3)|
|Duration||3 months||3 months|
|Ending Vit-D level in ng/ mL||9.58 ± 3.03**||37.95 ± 6.43**|
|* Two subjects were excluded having a vitamin-D3 level of >30 ng/mL. The subjects were unaware of the group they belong to. They kept their lifestyle and diet unchanged throughout the 3 months. ** All these levels were statistically significant <5% deviation|
Although this study used a small number of subject, it provides an option for patients to increase the D-level beyond sun exposure and supplement.
Vitamin-D brings in an all-in-one benefit package to treat acne. Along with a master controlling hormonal action, powerful microbial action, immunity modulation and ability to fight off the inflammation, dismantling the colonization of hair follicles by providing a healthy bacterial assembly that subdued the action of acne bacteria, i.e. Propionibacterium acnes (P. acnes).
Sensible exposure to small doses of Vitamin-D producing sunlight, you may get a completely natural treatment option for curing acne. Do not worry if you are not having sunlight as much as you like. Replenish your body with D-supplement and vitamin-D rich diet or consult your dermatologist for a topical treatment.